Vol 4, No 4 (2013)

Lack of efficacy of treatment of patients with atrial fibrillation (AF) is partly due to their low adherence, stipulatedby a lack of disease awareness among the patients. The article describes a technique of therapeutic training of patients with atrial fibrillation, developed on the basis of Ivanovo State Medical Academy and its influence on patients' awareness about the disease, their treatment adherence and quality of life. Schooling for patients with atrial fibrillation also led to a decrease in the number of applications for inpatient and outpatient medical care due to the worsening of arrhythmia. Positive dynamics of these indicators was noted early after training, and also 3 years after its closure.

The theory based on the supposition that for the effective treatment of diabetes patients should largely take responsibility for their health, is of no doubt. This is only possible if patients are properly trained to perform continuous monitoring of their disease and have at their disposal some modern easily manageable blood glucose meters that meet international standards and. The present article highlights the changes in the last revision of national guidelines related to the treatment of self-control, as well as existing modern demands in instrumentation for glycemic control.

Despite the facts, revealing the mechanisms of pathogenesis and enhancing the effectiveness of the treatment of cardiovascular disease (CVD), the latter continues to be the leading cause of death and disability in the population. In this regard, the search for new treatments for CVD remains the most relevant in modern cardiology. In the treatment of CVD many classes of drugs are used, among which are calcium antagonists (AA). This class of drugs has been successfully used in the treatment of patients with arterial hypertension (AH) and coronary heart disease [1-3, 5].CA are a heterogeneous group of drugs that have the similar actionmechanism, but differ in a number of properties, including pharmacokinetics, tissue selectivity, effect on heart rate, etc. The main feature of all is the ability of CA to reversibly inhibit calcium current through the slow calcium channels. These funds are used in cardiology from the end of the 1960s and have since become so widely popular that in most developed countries they hold one of the first places on the prescription rate of drugs used for the treatment of cardiovascular disease. This is due, on the one hand, to the CA high clinical efficacy, and on the other to a relatively small number of contraindications to their purpose and the comparatively small number of side effects. [1, 2, 4, 5].

The article in comparative aspect presents results of rating of psychological profile of 142 patients (all are men, average age 46,5±0,35 years) with arterial hypertension of stage I–III with high risk of cardiovascular complications having been studied after 6 months of dynamic observation against the background of conducted antihypertensive therapy with inhibitors of angiotensin converting enzyme (ACE).

139 patients with confirmed diagnosis of "dyscirculatory encephalopathy" (DEP) - including 120 men and 19 women, mean age - 47,1 ± 7,6 years were examined. Factor analysis showed that DEP is based on structural and functional state of the main arteries of the head. The greatest contribution to the DEP was made bythe pathologically changed intracerebral vessels (middle and posterior cerebral arteries), a slightly smaller one by vertebrates and carotid arteries (common and internal). It is shown that changes in the brain vessels are not only a consequence of atherosclerosis, but also are formed due to hemodynamic overload; vertebral influences play a role in anatomical features and functional status (angiodystonia). In most cases, hypertension in the formation of DEP is not paramount and decisive;often it only reinforces the importance of other mechanisms. Metabolic syndrome can be considered as an important component in the structure of the mathematical model of the DEP patient. Impact on its components should be included in a comprehensive treatment of these patients. Factor analysis confirmed the clinical significance of myocardial dysfunction in patients with DEP, making justified measures to improve the pumping function of the myocardium. Recommended analyses for patients with complex DEP laboratory and instrumental examination include: X-ray (X-ray, computed tomography) study of the spine, computed tomography and/or magnetic resonance imaging of the brain, Doppler ultrasound of the great arteries of the head,rheoencephalography, electroencephalography , cardiac ultrasound , biochemical blood tests (glucose, cholesterol and its fractions).