Cardiopulmonary relationships in patients with concomitant chronic obstructive pulmonary disease who were hospitalized for acute coronary syndrome

Abstract


Aim. To study cardiopulmonary relationships in patients hospitalized for acute coronary syndrome with concomitant chronic obstructive pulmonary disease (COPD). Materials and methods. Based on having/not having of COPD exacerbation on admission. 52 patients (29 men and 23 women) were divided into 2 groups: group 1 (n=33) with COPD exacerbation and group 2 (n=19) without COPD exacerbation. Patients examination inclused spirometry with bronchodilator test and identification of serum troponin T (TnT) levels. Results. In 30 patients TnT levels confirmed a development of acute myocardial infarction (AMI) and in 22 patients TnT levels were below the diagnostic threshold. In patients with AMI mild-to-moderate COPD was prevalent (70.0% out of all cases) and exacerbation of COPD was diagnosed in 76.7% of patients on admission. TnT levels in patients with both AMI and an exacerbation of COPD were significantly higher compared to those in patients without COPD exacerbation: 0.78±0.17 and 0.59±0.14 ng/ml, respectively (p=0.014). Patients without AMI and with COPD exacerbation had higher TnT levels compared to patients without COPD exacerbation: 0.19±0.08 and 0.11±0.04 ng/ml respectively (p=0.002). Conclusion. Thus concomitant COPD, especially with acute exacerbation, is associated with an increased risk of AMI in patients hospitalized with acute coronary syndrome.

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About the authors

Bahram H. Iskenderov

Penza Institute for Advanced Medical Education - branch of Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation

Email: iskenderovbg@mail.ru
8A, Stasova st., Penza, 440060, Russian Federation
D. Sci. (Med.), Professor, Professor of the Department of Therapy, Cardiology, Functional Diagnostics and Rheumatology

Natalya V. Berenshtein

Penza Institute for Advanced Medical Education - branch of Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation

8A, Stasova st., Penza, 440060, Russian Federation
Cand. Sci. (Med.), Associate Professor of the Department of Therapy, Cardiology, Functional Diagnostics and Rheumatology

Tatyana V. Lokhina

Penza Institute for Advanced Medical Education - branch of Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation

8A, Stasova st., Penza, 440060, Russian Federation
D. Sci. (Med.), Head of the Department of Therapy, Cardiology, Functional Diagnostics and Rheumatology

Marina G. Ivanchukova

Penza Institute for Advanced Medical Education - branch of Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation

8A, Stasova st., Penza, 440060, Russian Federation
Graduate student of the Department of Therapy, Cardiology, Functional Diagnostics and Rheumatology

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